At2g04530.1/MSA

MQLSSSFPISPPKIFPSTKHHKPPVITHQLAAQI--QSNRRHFVSPVKVSGYFSSI SRAIEEEEEYRKARAAVNRKGVELESYAIEG- ISVGGHETCVIVPELKCVFDIGRCPSRAIQQKFLFITHAH LDHIGGLPMYVASRGL--YNLE--PPKIFVPPSIKEDVEKLLEIH--- RTMGQVELNVELI-PLA--- VGETYE-LRNDIVVRPFATHHV-IPSQGYVIY SVRKKLQKQYAHLK--GKQ--IEKIKKSG-VE-IT--DTILSP- EIAFTGDTTSEYMLD---PRNADAL--RAKVLITEATFLDESFSTE-HAQAL-GHT HISQIIENAKWIRSKTVLLTHFSSRYHVEEI-REAVLKLQSKVSAK-- VIPLT-EGF--- RSRYS >gi|104781771|ref|YP_608269.1|	  320 residues, 50 /line  Ribonuclease Z [Pseudomonas entomophila L48] MDLQFLGT SSGVPT--KARNVSATAVIEATGHGWYLVDCGEGTQHQLL RS--PLSMRDLRAIFITHVH GDHCFGLPGLLASAGM--SGRK---A--PLPLIMPTALHDWVRQGLAAS--- DTYLPFELQLQAL-ET -FDGF--TCGNIQVGKVELSHR-VPSYGFVFD EQDPEPRLDTARLQADGVPAGPL--WGQLARGMTVE--H-EG--RQLDPQHYLQPQRPPQ RIIVCGDND---RPE---LLAELAK--GVDVLVHESTFTEP--VVE-RAQATFGHS TAAAVARFAEAAQVPNLVLTHFSARYQGAGAA---RGSSIEDVREEALAH--YR-G NLVLA-QDLQRYHLARDGRLVEV- L >gi|26990736|ref|NP_746161.1|	  319 residues, 50 /line  metallo-beta-lactamase family protein [Pseudomonas putida KT2440] MDLLFLGT SAGVPT--KARNVSATAVIEASGSHWYLVDCGEGTQHRLL HT--PLSIRDLRAIFITHVH GDHCFGLPGLLASAGM--SGRT---Q--PLEVILPAVLHDWVRQGLVAS--- DTFLPFELRLLPV-EE -LIAW--RSETLQVTTVQLSHR-VPSVGFVFT EINPEPRLDIQRLDAEGITRGPL--WGELAKGLTVT--Y-DG--QLLNGNDYLRPSRPPR RVIVCGDND---KPE---LLAAVAR--GADVLVHEATFTQA--VVE-RTGGTFGHS TAAEVARFAEAAGVRNLVLTHFSARYQNDPRRSPHIDNVRDEALAH--YS-G QLTLA-QDLQRYHLGRNGLLEAS- A >gi|146283279|ref|YP_001173432.1|	  337 residues, 50 /line  metallo-beta-lactamase family protein [Pseudomonas stutzeri A1501] --MPVDLLFLGT SSGTPT--RARNVSALALLEETGKAWYLIDCGEGTQHRLL RT--PLSLHDLRAICITHVH GDHCYGLPGLLASAGM--MGRK---A--PLTIIAPQGIETWVRATLSMS--- QSWLSYELDFHAV-ET -LDEW--RSPNMRIEATELSHR-VPCYGYSFS EARPDPRLDIERLEHDGVPRGPL--WGQLARGFDIE--H-EG--RVLRSHDYLSFSRSPR RIVVGGDND---RPD---LLAEACR--DAQLLVHEATYTEA--VAN-DARNDFGHS TAATVARFAQAVGLPNLVLTHFSARYQKHVGRGHSIEDLRAEAAAL--YA-G QLLLA-EDYLRLHLGKDGLLTVVEP--- --PSTSRPPRRDGESRA >gi|110669277|ref|YP_659088.1|	  318 residues, 50 /line  Ribonuclease Z (RNase Z) (tRNA 3 endonuclease) [Haloquadratum walsbyi DSM 16790] MRATFLGT GGAVPT--TERGPSAFFVE--RDGERLLFDCGEGTQRQMM RF--GTG-FSLSHIFVTHLH GDHILGIPGLIQTLDF--NDRT---D--ALAIHGPPGSKPHLRHLVETA--- GYRPGYPINIREI-RPG--- -SVAV--DTEEYIIRSFETSHRGVTSIGYALI ESDRKGRFNRDRAESLGVPVGPK--FGRLHDGESVK-LA-DG--SIVHPEQVVGDSRPGR RVVYTGDTR---PTE---TTVEAAN--NADLLVHDATFAAD--RAS-RAKQT-GHS TAQEAAQIATRADARQLALTHVSSRYAGD--VTPLESDATAA--FDGQ RAFVP-DDGYTLDIPFPDADDNHLSD-- --NIP >gi|115646024|ref|XP_001202680.1|	  333 residues, 50 /line  PREDICTED: hypothetical protein, partial [Strongylocentrotus purpuratus]

---REAWLIDCGEGTQIQLM RS--NVRPGRITKIFITHLH GDHSFGLPGLMCTLSAAFMDPDREGS--IMHIYGPQGLRKYVRVSLELS--- RSELSYSYVVHEL-QVPDTEFPHD-WETWKPS HEAEGSLHPNEKTGQAIFM-TADGTYKLH--EDDNFIIHAATISHR-VPCFGYVFL EKPQPGRLDAEMLKARGIKPGPL--YARIKAGHEIE-AP-DG--SVIKPQDVVGPTRQGR KIVILGDTK---ESS---RIIPIAM--NADVLVHEATLADE--HHD-LCIGR-GHS TPAMAGQFAAQIQCEHLVITHFSQRYYPLSHQGKEGDETVQKLLDQTRAT--FPGG KVTAA-EDFLTISVPARR-- - >gi|116333981|ref|YP_795508.1|	  317 residues, 50 /line  Metal-dependent hydrolase of the beta-lactamase superfamily III [Lactobacillus brevis ATCC 367] MEIEFLGT GAGSPG--KFRNVTSTALRLL---DERNSVWLFDVGEATQHQIL RT--TLKPRKIDKIFITHLH GDHIFGLPGLLSSRSF--QGG---DA--PLTIYGPKGIRNFVEVSLRVS--- ETKLSYKIRYQELT-- ---TDGLVF--EDGKFRVYAQHLDHR-IECFGYRIE EKDHPGELQVEQLQAAKIPSGPV--YGQLKAGKTVT-LP-DG--RVINGADFLGPAQPGR IVAILGDTR---QTP---NAEKLAI--NADVLVHESTFAK--GESK-LARSY-YHS TNIQAAELAKRMHVKQLLLNHISARYTG--KM---AAELQHQAREV--FK-- QTRVV-KDFDEIEVPFEKLTKEGT ---PS >gi|116618569|ref|YP_818940.1|	  318 residues, 50 /line  Metal-dependent hydrolase of the beta-lactamase superfamily III [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] MQLEFLGT GSGQPS--KFRNVTSIALRLL---DERNAVWLFDVGEATQHQIL KT--TLRPRKVEKIFITHLH GDHIFGLPGFLSSRSF--QGAD-KNE--PLTIYGPKGVKEFVQTALRIS--- ETRLSYPIEYVDLT-- ---E-GVIF--EDHTFQVVAAPMRHR-IETWGFRVI EKDHPGELLVDKLKQGNIPSGPV--YGQLKAGKTVT-LP-DG--RIVNGHDFIGKAQKGR IVTFILDTR---PND---NVEWLAK--NADVLVHESTYGSSEEEAK-MAKAH-AHS TSANAASVARRAHVNKLVLTHLSARYIG--PM---VKELIHDVRRN--FA-- NTYVA-RDFDIIDIPFKKDSNES- K >gi|90962068|ref|YP_535984.1|	  317 residues, 50 /line  Ribonuclease Z [Lactobacillus salivarius subsp. salivarius UCC118] MELEFLGT GAGSPS--KSRNVSAVALKLL---DEIKKIWLFDVGEGTQHQIL NT--TIRPRKIDKIFITHMH GDHIFGLPGFLSSRSF--QGGE-KMG--PLTIYGPKGISDFVNISLKVS--- QTKLSYELNFVELE-- ---EEGLLL--ENDRFKVYAYKLDHR-IECWGYRIE EKDYPGELQVEKLREAKAPSGPI--YGRLKAGEVVT-LE-DG--RTIDGKDFIGKAKKGR IVTILGDTR---QTP---NLKLLAK--DADVLVHESTFGK--GEGK-LARNY-HHS TCVQAATLAKEVGVKQLLLTHISARYVG--KM---VKVLEKEAKKV--FP-- NTKVV-KDFDTFNIPFPERKDDE- Q >gi|116491094|ref|YP_810638.1|	  325 residues, 50 /line  Metal-dependent hydrolase of the beta-lactamase superfamily III [Oenococcus oeni PSU-1] MELEFLGT GAGQPS--KQRNVTSIALRLL---DERNEVWLFDVGEATQHQLL KS--NTRSRKVTKIFITHMH GDHIFGLPGFLTSRNF--QGSELIDGGKPT--DVTIYGPAGLQQYVFSVLRAA--- QVRLQYRINFIQV-R- PGIIF--EDQQFAVSAFPMNHG-IEDYAYRVV EKDTVGQLQVEKLLKLGLKSGPL--FGKIKAGEIVK-LE-NG--LTINGKDFLGPDRPGR IIAIVLDTK---DTP---EIIKAAE--QADVLVHEATYGAE--NSI-MAKRH-GHS TSLQAAEHARAAHAHQLILTHISARYLG--KM---ADQLVKQAKNV--FR-- PTYIA-HDLEIFDIPAKKSERKDKID-- ---VG >gi|116494840|ref|YP_806574.1|	  320 residues, 50 /line  Metal-dependent hydrolase of the beta-lactamase superfamily III [Lactobacillus casei ATCC 334] MEIQFLGT GAGSPS--KSRNVSSLALKLL---DERNEVWLFDAGEGTQHQIL QT--AIRPRKIAKVFITHLH GDHIFGLPGFLASRSN--QGGT---D--PLTIYGPSGIEDFVKTSLKVS--- QSHLSYPLKFVLLQ-- ---HPGVAF--EDQTFKVTFDRLDHR-ITSFGFRIE EKPHPGELLIDKVRAAKIPSGPV--YAALKAGETVT-LP-DG--RIFDGHDFIGPAQPGR TVAIFGDTR---MCN---RALPLAA--GADVLVHESTFGPD--ESQ-LAKQY-YHA TNVQAAALAKRAGVGRLLLNHISARYLS--PGV---AMLEKTARQI--FP-- NTHVV-KDFEEINIPFRSEQSEPAVT-- --VKS >gi|121536418|ref|ZP_01668196.1|	  314 residues, 50 /line  ribonuclease Z [Anaeromyxobacter sp. Fw109-5] ---MLRLTFLGT SAAQPT--IHRNLTGLAVR--RDRELFLVDCGEGTQRQMI RF--GTG-FDVDAIFFTHFH ADHYLGAIGFLRTLSM--QGRT---T--AMDVYGPRPAKRLLDVMLFTG--- TERLAFDVRIHEV-A- PGADV--RRDGCLMRPFATVHR-TPSVGWALV EDERPGRFHPERAAALGVPKGPL--YGALQRGEAVT-LG-DG--RVVQPEQVVEPRRRGR TVVVTGDTR---PCA---GTIAAAR--GADLLVHDCTFGDA--EQA-RARET-MHS TAREAAGVAREAGVRELVLTHLSTRYDR--DWQPLVDEARAE--WA-G SLSVA-SDGMTIEVPLPDELAGAPAP-- G >gi|124009422|ref|ZP_01694099.1|	  315 residues, 50 /line  ribonuclease Z [Microscilla marina ATCC 23134] ---MFQVTILGS GAALPV--IAPDFRRYPTSQIVSLP--HTHLLIDCGEGTQMRLQ EL--KIRINRIKHIFISHLH GDHYLGLIGLLSSMHL--NKRN---Q--DLYLYGPPGLAEIISVQLKYS--- QTRFNYKIHFKEL-KV --GESEEIM--SDGMFTIRTIPLSHR-IPCNGFLIQ ENPKKRKIIKEKIPE-EIWDWQY--AKTLQKGDDIL-DP-EG--KVLISAKDVTVQPKSR AYAYCSDTA---YHE---PIIEHIK--GVDMLYHEATFTSE--EID-RATDT-FHS TARQAATIATKAEVGKLLIGHFSSRYRN--YLDPLIKEAREV--FS-- ESYLA-VEGSTFVLEKELMPV--- E >gi|125564150|gb|EAZ09530.1|	  365 residues, 50 /line  hypothetical protein OsI_030762 [Oryza sativa (indica cultivar-group)] MAATSLLSLP--SLRLTHRLLVPA SSSAPA--SRSQFQTLAAKKAAVATGTGEGGGGGRGAGGGLLSVLDRAMADEEEYR RARAQVQRKGVEVEGYAIEGVSVGGHETCVTVPSLNVAFDIGRGPLFAVSQDYLFITHAH LDHIGGLPMYIATRGL--YNLK---P--PV-VFVPPCIKDDVEDLLQIH--- RRMSQVDLKVELV-ALD--- LGETFE-IRNDLVARPFETHHA-IPSQGYVIY SVRRKLKKQYAHLKGNQIMK-MK-QS--GAEITDTILYP- EVAFTGDTKSDFILD---PQNADAL--RAKVLITEATFLDDQIDVD-HAREH-GHM HLSEIMEHSQWFRNKAIVLTHFSNRYSLEDI-RQAVSKLQSKLSSK-- VVALT-EGF--- KSDYR >gi|126179500|ref|YP_001047465.1|	  317 residues, 50 /line  ribonuclease Z [Methanoculleus marisnigri JR1] MVRIAGETLHVHFLGT AGALPS--PQRNPSCLLIR--RGSDTLLFDCGEGAQQQMM RA--RTG-FTVNAVFITHWH ADHFLGVFGLVETLAF--MGRT---D--PLPIYGPPWVGEFVDLVQRIS--- RHTRGFSVTAHVL-E- HGSVV--PFNGYTVRAFTTLHG-IPGLGYVLE EDERPGRFNRERAIELGVPPGPL--FGRLQRGEEVRVVR-DGVETAVRPADVMGEPRPGR KIVYTGDTR---PLQDQPGIAALIR--GADLLIHDATFDDQ--ESD-RARDV-LHS TAGEAGEAATALGARMLALMHISSRYAST--ANHIHDAKRQ---YE-G DVILP-ADLAVLEIPYRS-- - >gi|149199049|ref|ZP_01876089.1|	  352 residues, 50 /line  Metal-dependent Hydrolase of the beta-lactamase superfamily III [Lentisphaera araneosa HTCC2155] ---MLMVFIVEEKYTSRGFILQFHFLGT SAGSPT--VERNVTALGFMPRGRKNWWLFDCGEGTQQRLL RS--SLSLPKLNKIFITHMH GDHCYGLFGLLTSRGLM-SGGE---E--AVHIFGPKGIKEMIKTVLKLS--- YVNLSAPLTFTEFDE- AGDLF--EDDEFIVSNVRLSHD-VPSWGYVVK EKDRPGSFDSAKAIRDGIKPGPI--YSKLKNAEMVT-LE-DG--REVNGADYVGETQKGR VALIGGDND---RPQ---LFGDALK--GAAVMIHEATHTEEA-MAG-LSFRS-RHS TAKRVAEVAEENQVKNLVLTHFSPRFITKKRKG---MKCVDEIEDEAKEF--FH-Q DLHMA-RDYDVYELDRESKLKLIDSRYRKDH- KSLNK >gi|15669696|ref|NP_248509.1|	  324 residues, 50 /line  hypothetical protein MJ1502 [Methanocaldococcus jannaschii DSM 2661] MR--NNSKKMIIMKLIFLGT GAAVPS--KNRNHIGIAFKFG--GEVFLFDCGENIQRQML FT--EVSPMKINHIFITHLH GDHILGIPGLLQSMGF--FGRE---K--ELKIFGPEGTKEIIENSLKLG--- THYIEFPIKVYEI-YT --KEPITIY--KEENYEIIAYPTEHG-IPSYAYIFK EIKKP-RLDIEKAKKLGVKIGPD--LKKLKNGEAVK-NI-YG--EIIKPEYVLLPPKKGF CLAYSGDTL---PLE---DFGKYLKELGCDVLIHEATFDDS--AKD-AAKEN-MHS TIGDAVNIAKLANVKALILTHISARYDK--EEYFNLYKMNVKQYN--ESF-- KIIIS-EDLKSYDIKKDLL- G >gi|22325471|ref|NP_178532.2|	  354 residues, 50 /line  CPZ [Arabidopsis thaliana] >gi|51011089|ref|NP_001003503.1|	  372 residues, 50 /line  elaC homolog 1 [Danio rerio] --MSMDVTFLGT GSAYPS--PHRGASALVLRT--EGENWLFDCGEGTQIQLM KS--TLRAGKISKVFISHLH GDHLFGLPGLLCTISL--NLNP---QPDQPPPCVDIYGPRGLRLFIRVALQLS--- GSQLLFPYAVHEL-QPSDEQCPEEGRLSPALT TASETLH-PQERPGRTVHPDPDTDCYHLI--DDKQFVVKAFKLFHR-VPSFGFSVE ERERPGRLNTDLLKELGLKPGPL--YGRLKNGQSVT-LD-SG--RVLTAGEVLEPPLKGR KVCVFGDCSA-PLGE---GFKRACY--GADVLVHEATLENG--QQE-KAVEH-GHS TPGMAAAVALTCEAKTLVLHHFSQRYKPENLRRDDDEDDVSELKRQAELVLQGSRT DVILA-EDFLTLPVVLKRNST--- T >gi|72161928|ref|YP_289585.1|	  318 residues, 50 /line  ribonuclease Z [Thermobifida fusca YX] -MSTRELIVLGT SSAVPT--KRRAHNGYFLRWD--GHGILFDPGEGTQRQMR YA--GISAHDITRVCVTHFH GDHSLGLPGVIQRIAR--DGVT---H--PVRVAYPAAGQEYWER-LRYA--- TSFVDTEVIEAQPL-- -AGDEVVVS--GEDEFTVTALPLDHS-IPTYGYRIA EPDRVHML-ADRLAARGIR-GPA--VGRLKAEGFLI-DA-AG--NRVELADY-SVVRPGQ VFAFVMDTG---VCD---TAVRLAE--RADLLVIEATFLNA--EAE-LAARY-RHL TAGQAGMIAAQAGVRRLVLTHFSERYGR--EE---EDRFIAEAAAC--FS-G EIVLA-QDVMRVAVPSRRSEGGGTVA-- ---GA >gi|85081287|ref|XP_956690.1|	  359 residues, 50 /line  hypothetical protein [Neurospora crassa OR74A] ---MAPSPPQQPAPGS QSQPKP--AKTLTFATPLPQSARSDILEWSLPKPFSHYIL TG--KSRAAWHTSFVIPQLNLLLDAGL-VINKSRPKHIFITHGH NDHALSSPVFIKRE---D--PPDFHCPVGMKQVLEDYLRANTMLNLGG LIAPRPGKELPLEIRDPETGEVVRSEIRPTHVTYGLEAGDVV-- --PLR--RTKNISAVAFACDHT-VPCLGYLFQ QTTHKLKPEFAK-LPPKEL--KAIRASGQELT--APVTSP IFAFLGDTT---TKT---LEEEPMRGWLTNDKLPVVITECSFLYE--EHRAQAEKT-KHT IWADLEKVIRKYPETTFVVMHFSLRYSV--GQV---RRFFKERAEG--LD-- NVVVW-VDGEGEDGDDVGGEGE-- MGDED >gi|86606310|ref|YP_475073.1|	  324 residues, 50 /line  ribonuclease Z [Synechococcus sp. JA-3-3Ab] --MTDPNAIRVTFLGT SSGMPT--RQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLL RL--D---ELRPSQLRRIFITHMH GDHIYGLPGLLASCGL--GSTP---Q--HIDIYGPPGLEEYLKTVLRYS--- ESRIPYSFRVHTV-E- TGLIL--QDPEYWVFCAPLDHR-VPAFGYRVV EQDRPGTFDVAKAQADGIPPGPL--YGQLKAGQSI--LW-QG--RWFHGRDYVGAPIPGR KFSYCTDTI---FCR---NAVDLSR--AADLVIHEATYAEA--DRE-LAERA-KHS TAAMAARVAAEAKAQTLILTHFSPRYTS--EGPITLEDLLAEARAI--FP-- NTILA-RDRMTYEIPRRSPAPLPVG--- V >gi|88602980|ref|YP_503158.1|	  316 residues, 50 /line  Ribonuclease Z [Methanospirillum hungatei JF-1] MDIIAGETLQIFFLGT SGALPT--ISRNLPCILLKWG--SHDLIFDCGEGAQRQMM KA--RAGFSP-EVIYISHWH ADHFLGVIGLLQTMSF--NGRE---Q--PLMIVGPDCVHEMVNDIKGLC--- RTRLSFPVESQKV-R- AGDLL--IYEGYSIRVFAADHG-IPGVGYIFE ENMRPGRFNRERAIELGIRPGPL--FGKLQRGSSVT-ITVDGEERIITPEMVMGPMRPGR KVIYTGDTRP-V-LS---ELADIGD--DADLLIHDATFDHQ--EEE-RAIEF-MHA TAAEAGMVAHTLKAHRLALFHFSTRYTS---ADNHVSDAKTH--FS-- GDILAPDDLTVFDIPFRDE- - >gi|93279549|pdb|2FK6|A	  320 residues, 50 /line  Chain A, Crystal Structure Of Rnase ZTRNA(THR) COMPLEX MELLFLGT GAGIPA--KARNVTSVALKLL---EERRSVWLFDCGEATQHQML HT--TIKPRKIEKIFITHMA GDHVYGLPGLLGSRSF--QGGE---D--ELTVYGPKGIKAFIETSLAVT--- KTHLTYPLAIQEI-E- EGIVF--EDDQFIVTAVSVIHG-VEAFGYRVQ EKDVPGSLKADVLKEMNIPPGPV--YQKIKKGETVT-LE-DG--RIINGNDFLEPPKKGR SVVFSGDTR---VSD---KLKELAR--DCDVMVHEATFAKE--DRK-LAYDY-YHS TTEQAAVTAKEARAKQLILTHISARYQG--DASL---ELQKEAVDV--FP-- NSVAA-YDFLEVNVPRGKLAAALE -HHHHH--H >gi|124541043|ref|ZP_01703923.1|	  315 residues, 50 /line  ribonuclease Z [Methanococcus vannielii SB] MKLTFLGT GAAVPT--KYRSHPSVALKFD--GEIFLFDCGENTQRQII FT--DVSPMKINNIFISHLH GDHILGIPGLLQSIAF--QGRK---K--PLNIYGPPETKEMIKNMLKIG--- YHSIDYPINIHEA-SI --ESPEMIIASSNNSNGNNYEVYTFPVKHS-VPSISYLFK QIKKP-QMDIKKAETLGIEIGPD--LKKLKDGFSIQ-LK-NG--KVITPKDVTIPPKKGY CIGYSGDTI---PID---EFGKFLKYHGCNVLIHEATFDSS--MQK-NAVDT-MHS TILDALDILEKSGARTLIATHISARYDD--IMSFERDIVKFKEKN--PEI-- EILIA-EDFLEYVLK- - >gi|134045752|ref|YP_001097238.1|	  314 residues, 50 /line  ribonuclease Z [Methanococcus maripaludis C5] MKLTFLGT GAAIPT--KYRAHPSISLKFD--GEIFLFDCGENTQRQII FT--DVSPMKINNIFISHLH GDHVLGIPGLLQSIAF--QGRT---K--PLNIYGPEETAKMIKNILNVG--- YHSIDYPINVYEI-SS --KTSEKII--STDNYDVFSFPVVHS-VPAVAYVFR QVKKP-RMDLEKVNKLGIEIGPD--LKRLKDGYNVE-L--NG--KIITPEDVTLPPKKGI CVGYSGDTI---PLN---EFADFLKELKCTILIHEATFDKT--MDK-NAKET-LHS TVHDALNIAKRSGANTVILTHISARYDE--LSAFEKDVVEFKVEH--PDL-- HVLIA-EDLMEYSLKGKWVK M >gi|145642550|ref|ZP_01798089.1|	  322 residues, 50 /line  ribonuclease Z [Methanococcus aeolicus Nankai-3] MKIIFLGT GAAIPT--KHRNHSSVGIKYD--GEVFLFDCGEGTQRQMI YT--DISPMKINNIFISHLH GDHILGLAGLLQSIGF--NGRT---E--PINIYGPPEIKNTIENILKIG--- YHSINFKITVHEI-NS --KKPMKII--DSEKYMAYAYPVNHS-IPCYAYILK EKKKP-QLNLKKAMELGVEVGPD--LKSLKDGNEVK-LK-NG--KIIYPNDVLLPPKDSM CVAYSGDTM---PIE---DFGEFLNSIGCTVLIHEATFGSS--KKN-NAVET-MHS TIEDAVNIGKIACVDTVILTHISARYDD--NIEIYYNEIENIIKNNNEYNDNNF-- KIIVA-EDLMEYDLKNKETIK--- K >gi|126320779|ref|XP_001364239.1|	  368 residues, 50 /line  PREDICTED: similar to D29 [Monodelphis domestica] --MSMDVTFLGT GSAYPS--PTRGASAIALRF--EGACWLFDCGEGTQTQFM KS--QLKAGRITKIFITHLH GDHFFGLPGLLCTISL--QNSS---SASKT--PMEIYGPVGLRNFIWKTMELS--- HSELTFPYIVHEL-VPTEDQCPPG-ELKDFSS LDKMDSI-PKEIQGRTILLDSAEESYVLV--NDEQFLVKAFRLFHR-IPSFGFSVA EKERPGRLNAQKLKDLGVPPGPA--YGKLKNGVTVV-LE-NG--VKVSPQDVLEKPIPGR KICILGDCSG-VVGD---GGVKLCF--EADLLVHEATLDNA--HMD-KAKEY-GHS TPQMAAEFAKMCKVKKLVLTHFSQRYKPHLLSGEGEADDIRELKKQAESVLDFQ-- EVTLA-EDFMVIDIPKKKTISI-- T >gi|62859611|ref|NP_001017028.1|	  363 residues, 50 /line  elaC homolog 1 [Xenopus tropicalis] --MSMDVTFLGT GSAYPS--PCRGASAVVFRT--EGECWLFDCGEGTQTQFM RS--PLKAGRITKIFITHLH GDHMFGLPGFLCTVSL--QCGC---TPSKQ--LVDIYGPVGLREFVQRSLEIS--- HSQLVFPYVVHEL-VPSPDQCPAE-EFKDFSS RGGESCL-ATEEQGRTIYASPEDGSYELI--ADEQFTVKAFKLFHR-IPSFGFVIE ERERPGKLNMQKLKELGIQPGPV--CGKLKLGATIT-LD-NG--QKVSPSDVLGDPIPGR KVCILGDCSG-VIAV---GGAKLCC--DADVLIHEATLDDS--QMD-KAKEH-GHS TPKMAADFANLCCARKLVLTHFSQRYKPPGLVTEGD-EDVTVLKQQAESALPGQ-- HVTLA-EDFMTITIPMKKQ- - >gi|73945502|ref|XP_849493.1|	  374 residues, 50 /line  PREDICTED: similar to Zinc phosphodiesterase ELAC protein 1 (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1) (Deleted in Ma29) isoform 2 [Canis familiaris] --MSMDVTFLGT GAAYPS--PTRGASALVLRC--EGECWLFDCGEGTQTQLM KS--QLKAGRITKIFITHLH GDHFFGLPGLLCTISL--QSGS---VVTKQ--PIEIYGPAGLRDFIWRTMELS--- HTELVFPYVVHEL-VPTADQCPTE-EQKEFTH VNEMDSL-PKEGQGRTILLDSEENSYLLV--DDEQFVVKAFRLFHR-IPSFGFSVV EKKRPGKLNAQKLKDLGVPPGPA--YGKLKNGISVV-LD-NG--VTISPQDVLKKPIVGR KICILGDCSG-VVGD---GGVKLCF--EADLLIHEATLDDA--QMD-KAKEH-GHS TPQMAAAFAKLCQAKRLVLTHFSQRYKPVALAREGEADGIVELKKQAESVLDLQ-- EVTLA-EDFMVNKFRSRSETIFLM RLTCL >gi|120555084|ref|YP_959435.1|	  323 residues, 50 /line  Ribonuclease Z [Marinobacter aquaeolei VT8] MEFTFLGT SAGTPT--RSRNVTGLALCLSGPKPWYLVDCGEGTQHQLM RT--RYSVMQLRAMFITHIH GDHIFGLPGLLTSASM--LGRT---E--PLDIIAPPQVRRFIDAVIENS--- DSSLSYPLNFINSE-- ---APDFYW--QDDHLGVTNVALSHR-VPCRAYVFT ERNLERQLQKEKLVADGIEPGPQ--WGDLQKGKDVL-LD-DG--RLLRSNDYTHIPRTAR KIIVGGDND---TPE---LLKDACQ--GTHVLIHEATYTQD--VADRVGPWP-QHS SAQQVARFAQATKLPNLVLTHFSSRYQSAPGGSPHINQLAAEALQH--YK-G QLFLA-RDFDTYRLEKDFQLHKVD ---HN >gi|126667041|ref|ZP_01738016.1|	  322 residues, 50 /line  Metal-dependent Hydrolase of the beta-lactamase superfamily III [Marinobacter sp. ELB17] MEFTFLGT SAGTPT--RSRNVTALALSHSGHKPWYLVDCGEGTQHQLL RA--HYSVMQLRAIFITHIH GDHTFGLPGLLTSASM--LGRT---E--PLDIVAPVQTQRFINATLENS--- DSSLGYTLNFINSE-- ---APDFCW--KDQDFGVTNVALSHR-VPCRAYVFT ERNIERQLLQDKLNEDGIEPGPN--WGELQKGNDVM-QE-DG--RLLRSADYTQTPRVAR RLIVAGDND---DPT---LLTGACK--GSHALIHEATYTQD--VADRVGPWP-QHS SAEQVGRFAQQAQLPNLVLTHFSSRYQSAPGVTPNINQLAAEAMQH--YL-G PLFMA-RDFDAYRLEKDLSLICLS A >gi|113474494|ref|YP_720555.1|	  321 residues, 50 /line  ribonuclease Z [Trichodesmium erythraeum IMS101] MQITFLGT SSGVPT--RSRNVSSIALRLPQRAELWLFDCGEGTQHQFL RS--DLKVSQLSRIFITHMH GDHVFGLMGLLASCGL--GGNV---K--SVTLYGPPALEDYLQAGLRYS--- QTHLAYPIKVHKS-K- PGVIY--EDDEYVVSCAYLKHR-VTAFGYRVT EKDRPGHFNVEKAKALGIPPGPI--YRKLKQGEFVT-LP-DG--RKINGADLCGAPHVGR KFVYCTDTV---FCD---GAVELSQ--GADLLVHEATFSHQ--DAE-MAFQR-LHS TSTMAAQVALAAGVKHLMMTHFSPRYAP--GNSVLLDDLLQEARAI--FP-- NTDMA-YDFLSYEIPRWNEVSQLLAK-- --ARS >gi|119490850|ref|ZP_01623133.1|	  315 residues, 50 /line  ribonuclease Z [Lyngbya sp. PCC 8106] MQITFLGT SSGVPT--RSRNVSSIALRLSQRAELWLFDCGEGTQHQFL RS--DLKISQISRIFVTHMH GDHVFGLTGLLASCGL--AGNV---K--RIDLYGPPGLQEYLQASLRFS--- QTHISYPFTVHPV-Q- PGVVY--EDDEYIVSCQPLKHR-VTAFGYRIT EKDKPGRFNVDKAKALGIPPGPI--YAKLKQGGVVT-LA-DG--RKINGSQFCGEPIAGR KFVYCTDTV---FCD---SAVELAK--DADVLVHEATFAHQ--DAE-LAFQR-LHS TSTMAAQVALMAGVKKLIMTHFSPRYAP--GNAILLDDLLTEAKAI--FP-- NTDLA-YDFFSYEIPKLEETVAA- - >gi|126661173|ref|ZP_01732250.1|	  318 residues, 50 /line  ribonuclease Z [Cyanothece sp. CCY0110] MEITFLGT SSGVPT--RSRNVSSVALRLPQRAEVWLFDCGEGTQHQLL RS--DVKISQITRIFVTHMH GDHIYGLTGLLASCGL--AGSG---Q--PIEIYGPPELKDYLKACAKYS--- HFKLPHHIRFHPI-H- PGILY--EDKEFSVSCGQLKHR-IPAYGYRIA ESDRPGRFNVEKAKALGIPPGPV--YGELKQGKTVT-LE-DG--RRIRGQDLCGERETGR KVIYCTDTV---FCE---GAIALSE--DADVLIHEATFAHQ--DAQ-LAFDR-LHS TSTMAAQVALAAQVKQLIMTHFSPRYAP--GNALQLDDLLQEAKAI--FP-- NTILA-RDFMTYEVPRRSQIETSKI--- G >gi|16331469|ref|NP_442197.1|	  326 residues, 50 /line  ribonuclease Z [Synechocystis sp. PCC 6803] MEITFLGT SSGVPT--RNRNVSSIALRLPQRAELWLFDCGEGTQHQFL RS--EVKISQLTRIFITHLH GDHIFGLMGLLASSGL--AGSG---Q--GIEIYGPEGLGDYLEACCRFS--- STHLGKRLKVHTV-RE NGLIY--EDKDFQVHCGLLKHR-IPAYGYRVE EKQRPGRFNVEQAEALGIPFGPI--YGQLKQGKTVT-LE-DG--RRIRGQDLCEPPEPGR KFVYCTDTV---FCE---EAIALAQ--EADLLVHEATFAHQ--DAQ-LAFDR-LHS TSTMAAQVALLANVKQLIMTHFSPRYAP--GNPLQLENLLAEAQAI--FP-- NTRLA-RDFLTVEIPRRTADPAIAMSTPQA-- --SPA >gi|75908619|ref|YP_322915.1|	  345 residues, 50 /line  ribonuclease Z [Anabaena variabilis ATCC 29413] -MPSNHATI---EDI-ALNIARKRLENAVQITFLGT SSGVPT--RARNVSSVALRLPQRAELWLFDCGEGTQHQIL RS--DLKVSQLSRIFITHLH GDHIFGLMGLLASCGL--AGNV---Q--RVDIYGPSGLNEYIQSASRYS--- HTHFSYPIKIHTV-R- PGVIY--EDDEFTVTCGLLHHR-ITAFGYRVA EKDRAGRFDIEKAKELQIPPGRV--YGQLKRGETVT-LE-DG--RVINGAELCGPTEIGR KMAYCTDTI---YCD---GAVELAQ--DADVLIHEATFAHQ--DSE-MAFQR-LHS TTTMAAQTALAAGVRRLLMTHFSPRYAP--GNTIELKDLLQEARAI--FP-- RTDMA-YDFMTYEVPRRREPILSSV---SS-- --SSV >gi|113955240|ref|YP_731447.1|	  315 residues, 50 /line  Ribonuclease Z (RNase Z) (tRNA 3 endonuclease) [Synechococcus sp. CC9311] MQVTFLGT SSGVPT--RGRNVSSVALRLPQRSELWLFDCGEGTQHQFL RC--DLRLSQLRRVFITHMH GDHVFGLPGLLASLGL--GSTS---N--GVDLYGPDPLDAYLQGVLRTS--- STRIGYPLAIHRV-REA--- -AEQNTVVF--EDDDLIVTAAPLNHR-VPAYAYRAE QKPRAGRFDIDKARELQIPPGPV--YAALKRGESVT-LD-DG--RTIDGRTLCGPEQPGV SVVYCTDTV---FCE---AAVQLAQ--GADLLIHESTFSHA--EAD-MAFKR-QHS TSTMAAQTAAEAGVKQLALTHLSPRYAP--GNAVTADDLVAEASAI--FP-- NTILA-RDFLNVDVNPSK-- - >gi|116071259|ref|ZP_01468528.1|	  327 residues, 50 /line  Ribonuclease Z [Synechococcus sp. BL107] MKDRELTTLQVTFLGT SSGVPT--RARNVSAVALRLPQRSEMWLFDCGEGTQHQFL RS--ELRLSQLRRVFVTHMH GDHVFGLPGLLASLGL--AGNS--NE--GVDLYGPDPLESYLNGVLRTS--- STRIGYPLKVHRV-HDC--- -AENGTLVY--EDDDLMVRCTPLTHR-VPAYAYRVD QKPLAGRFDIAKAKDLQIPPGPI--YAQLKQGDTVT-LE-DG--RIIDGTTLCGPERPGV SVVYCTDTV---FCE---AAVDLAQ--GADLLIHESTFAHQ--ESE-MAYQK-MHS TSTMAAQTAAEANVGQLVLTHLSPRYAH--GNAVTPEDLLKEAQAI--FP-- NTCLA-KDFLTLEVKPRCNS L >gi|56752093|ref|YP_172794.1|	  393 residues, 50 /line  ribonuclease Z [Synechococcus elongatus PCC 6301] MQVTFLGT SSGVPT--RSRNVSAVALRLPQRAEVWLFDCGEGTQHQFL RS--ELRISQLRRIFVTHMH GDHVFGLMGLLASVGL--AGNP---E--RIDLYGPKPLRDYLQACAQHS--- RTHINYPLQIATV-Q- PGVIY--EDAEIVVSCAPLHHR-VPAFGYRIQ ERDRPGRFDVEKARSLGIPPGPI--YKQLKDGETVT-LE-DG--RQIDGRQLCGPTERGR SMVYCTDTI---FCE---SAIALAQ--DADVLIHESTFSDR--DRE-MAEQR-LHA TATMAAEVAKQAGVRQLILTHFSPRYAP--GNEQTLDDLLAEAQAI--FP-- QTMLA-KDFLSYDVPRRLAADADEPTEVPAVAKSPSQPEPSAIVPDSRRKPQITKEVLVA RFSGEGEPAHRAAYRYLRETCGVTPKGRSWEAVLAAFNSLD >gi|124026481|ref|YP_001015596.1|	  314 residues, 50 /line  Metallo-beta-lactamase superfamily enzyme [Prochlorococcus marinus str. NATL1A] MQVTFLGT SSGVPT--LNRNVSAMVLKPPQRSELWLFDCGEGTQHQFI RS--NLKLSQIKKIFITHMH GDHIYGLPGLLASIGL--AGSS---S--GIELYGPAPLKNFIDSCLYNS--- SSRLAYSLKFHRV-ENA--- -ANNKEILF--EDSELEVKTAPLKHR-IPSFAYRVN QKTRPGRFDIEKAKLKGIPPGPV--YADLQRGEEVR-LE-DG--RIFSGKEFCGPPRPGV SMVYCTDTV---YTE---SAIEISR--KADLLIHESTYSYK--ETE-MAYER-GHS TATMAAQIAAKANVDQLILTHLSPRYTP--GNQTCPNDLLNEAKAI--FP-- NTQLA-KDFLQIDLNKS--- - >gi|84517526|ref|ZP_01004875.1|	  327 residues, 50 /line  Metallo-beta-lactamase superfamily protein enzyme [Prochlorococcus marinus str. MIT 9211] -MIDHLRKLQITFLGT SSGVPT--RSRNVSALALRLPQRSELWLFDCGEGTQHQFL RS--DLRTSQLRRIFITHMH GDHIYGLPGLLASLGL--AGNS---S--GIDLYGPNPLSNYLNGVLKSS--- SSRISYPFQIHSV-EKV--- -AEDNQIVF--EDKDFIVRCKPLIHR-IPAFAYRVD QKPRPGRFNLEKAKAFNIPPGPV--FAKLKLGQQVR-LE-DG--RIINGKDFCGPQKAGK SIVYCTDTI---FSK---AAIQLAK--GADLLIHESTFADK--DTD-MAFQR-KHS TSRMAAQTAKEAGVGKLVLTHLSPRYAP--GNAFSPNDLLKEAKEI--FP-- NTLLA-KDFMQIDIEKPETVRD-- T >gi|148242938|ref|YP_001228095.1|	  333 residues, 50 /line  Ribonuclease Z [Synechococcus sp. RCC307] -MPWHHQ-SWGSQPAPLQVTFLGT SSGVPS--RSRNVSAVALRLPQRADLWLFDCGEATQHQFL RS--ELRVSQLRRIFITHMH GDHVFGLPGLLASLGM--AGTC---D--GVDLYGPEPLEAFVLSALQHS--- ATRIGYPLRFHPV-ESA--- -ANSGEPLL--IDGEFSVCCAPLKHR-VPAFGYRVQ QSERPGRFDIAKAKAMRLPPGPE--FARLKAGETVT-FA-DG--RRIDGRELCGPRQPGC SVVYCTDTV---FSE---RAVALAQ--GADLLIHEATFSHR--DAA-MAYQR-QHS TSTMAAQTAAEAGVQQLALTHLSPRYVP--GATESPDDLLQEAKAI--FP-- NTVLA-KDFLSIEVSTMACNS--- L >gi|33240879|ref|NP_875821.1|	  320 residues, 50 /line  Metallo-beta-lactamase superfamily enzyme [Prochlorococcus marinus subsp. marinus str. CCMP1375] MQITFLGT SSGVPT--RSRNVSALALRLPQRSELWLFDCGEGTQHQFL RS--DLRTSQLKKIFITHMH GDHIYGLPGLMASLGL--AGNS---L--GLDLYGPSALKGFLDGILKSS--- SSRISYPMKIHGL-ELE--- -SAENKIIF--EDNDFLVTCTPLIHR-VPAFAYRVD EKAKPGRFDVEKAKALRIPPGPI--YSQLQKGQIVK-LK-DG--RIFNGNDFCGPQRKGA SFVYCTDTM---FAQ---TALKLAN--GADLLIHEATFSHE--DSD-LAYQR-QHS TSTMAAQIASEANVGQLVLTHLSPRYAP--GNRISPNDLLSEAKSI--FP-- NTLLA-KDFLQIEIQKHATVRD-- T >gi|37523688|ref|NP_927065.1|	  317 residues, 50 /line  hypothetical protein gvip548 [Gloeobacter violaceus PCC 7421] MLLTFLGT SSGTPT--RSRNVTSIALQLPQRSSLWLFDCGEGTQHQVL RT--PLRLSQLEKVFFTHLH GDHLFGLVGLLASRALG-SAGT---T--PVKLYGPPGLQEYVRATLRYS--- DTHINYPIHFQTV-E- PGLVL--SEEGFTVLANALKHR-ISAFGYSVI EHDQPGRFDAERAAQLGIPFGPL--YGQLKAGRTVA-LP-DG--RTVDGRTLVGPERKGR KLTYCSDTI---YTP---SAIELAL--GADVLIHEATYCEA--DLN-LAERG-LHS TAAMAARVAREAKVRQLILTHFSPRYEA--GLAALRTEAEAI--FP-- NVRMA-EDFWRYEIKAVEAQLPKALV-- ---EQ >gi|52549192|gb|AAU83041.1|	  335 residues, 50 /line  metallo-beta-lactamase [uncultured archaeon GZfos26D6] MENTRCSRCTRWQKISLSYIRYNHL---LFCMLRITFLGT GGSTPT--PNRNPSAIAVN--REGELILFDCGEGAQQQMM RA--K-SGMKITSIFISHFH ADHVLGIPGLLQTMAL--QDRQ---E--PLEIYGPKQVDKFLYHLLALG--- YAGRNFEVKAIEL-R- PGDVV--RRAGYEIRVIKTVHN-IPSIGYVLE EDMRPGRFNREKAIELGIKPGPF--FSKLQSGRSIL-L--DG--KEIRPEQVVGPPRPGR KIVYTGDTR---PCD---SVIEASE--NADLLIHDSTLSEE--TKE-YAINY-MHS TALEAAEVAKKASVRKLILTHISARYSD--PGG--ASKLEEEARSM--FE-- NTEVA-KDLMTEEVGYRDG- E >gi|57641049|ref|YP_183527.1|	  314 residues, 50 /line  ribonuclease Z [Thermococcus kodakarensis KOD1] ---MLEVFFLGT GGIMPT--RERNVPAIALR--YKGEIILFDAGEGTIRQMN TA--KLSPMKVDKIFITHFH GDHYLGIPALIQTMNL--WDRQ---K--PLHIYGPKYTFQFVQNLLNSG--- FFRPGFDIHVHELGE- T--RL--KFGDYEIWSFKVEHG-IPALGYVFK EKDRRGKFLKEKLREYGLEEGPI--LGKLEREGKIE-W--NG--RIIRLEDVTGPRRKGL KIVYTGDTE---PCE---RVKLFSE--RADLLIHEATYLNP--GDR---GDS-YHS TVEEACDTARRAKVKLLALFHRAFRYSY--EDY--VEEALKICESL--GV-- RAVVP-RDFDVITFKSGTWELRNLLE-- --ERE >gi|62180883|ref|YP_217300.1|	  334 residues, 50 /line  ribonuclease Z [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67] -MVEILPVNHDALLCCGNLGLNDN--QTCMDKMELIFLGT SAGVPT--RSRNVTAILLHLQ--HPTQPGVWLFDCGEGTQHQML NT--AFHPGKLERIFISHLH GDHLFGLPGLLCSRSM--AGNP---H--PLTVYGPQGVREFIATTLRLS--- GSWTDFPLQIEEI-S- AGDIL--DDGLRKVTAFRLEHP-LECYGYRVV EHDKPGALNARALKAAGVTPGPL--FQALKAGKTVT-LA-DG--RQINGADYLAPAVAGK SVAIFGDTA---PCE---AALALAQ--GVDVMVHETTLDAS--MEE-KANAR-GHS STRQTATLAREAAVGRLIMTHISSRYDD--KG---CQRLLAECRAI--FP-- ATELA-YDFSVFPV-- - >gi|75759266|ref|ZP_00739366.1|	  318 residues, 50 /line  Ribonuclease Z [Bacillus thuringiensis serovar israelensis ATCC 35646] MRDRVLELEERKWNCIFRNW CRCSFK--RKERFSNALQLLEERGQTWLFDCGEATQHQIL HT--SVRPRRIEKIFITHLH GDHIFGLPGLLGSRSF--QGGT---T--PLTVYGPKGIKQFIEVALSVS--- TTHVKYPLEVVEITE- EGTVF--EDNEFYVETKRLSHG-IECFGYRIV EKDIQGALLVDKLLEMGVKPGPI--FKRLKDGEVVE-LE-DG--TILNGNEFIGPPQKGR IITILGDTR---YCE---ASRELAQ--DADVLVHEATFAAE--DEQ-QAHDY-FHS TSKQAASIALQANAKRLILTHISSRYQG--DT---YKELLKEAREL--FS-- NTEIA-TDLKSFPVEK - >gi|124005252|ref|ZP_01690093.1|	  314 residues, 50 /line  hypothetical protein M23134_07750 [Microscilla marina ATCC 23134] -MVEGHP-FRQWRKWTIPNT TFTIEG--YSRSGDKTFFYIPQLKLCLDAALAEG-- RQGDYVLVTHTH NDHIADIEYLASRNG--VQIYLPKASQNYLEEYIIARRCLNHSA PYNPRLRGSYSI--TGV--- AGGDTFYIG--KNDRYQVKVVNCEHS-IVCVGYAFA EKKQRLKPEYEALKQQKMAEGKMQEFGQLMAQK---KQ--EAKQKGETVEETYYQP LFVFMGDTHASVF-DNNAWLF--DYPTIITECTFLKP--VNEAYANER-CHT HWKHLKPHINQHPKCQFVLTHFSFRYTSQEIVNFFEQELTQSQT NNVLI-WLSSDTLLPQQHESK--- K